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Lab welfare charity guides experimental design

The National Centre for the Replacement, Refinement and Reduction of Animals in Research has further developed its online tool to improve the reproducibility of animal research.

The Experimental Design Assistant was built in collaboration with software designers and statisticians to help researchers design reliable experiments, the charity said in an announcement on 29 September. Since the initial launch of the tool in 2015, it has been adapted to include visual design in grant applications.

The EDA contains information to help reviewers and grant panels assess how robust the planned experimental design will be, by featuring the information sought by the funding bodies. For example, it includes guidance on sample size and measures to reduce bias, such as randomisation and blinding. It also includes a summary of feedback received to date on the recommended methods of statistical analysis and diagrams.

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